Dr. TM Janake Munasinghe

MBBS (Col), MD (Medicine)
Senior Lecturer Gr I Medicine
  • Qualifications
  • Qualifications

    • 1982- MBBS Second Class Honours, Faculty of Medicine, University of Colombo, Sri Lanka
    • 1989 -MD Medicine Postgraduate Institute of Medicine, University of Colombo, Sri Lanka

    Licensure and registration

    • 1983- Full registration  Sri Lanka Medical Council
    • 1991- Board Certified  Specialist in General Medicine 
  • Research & Publications
  • Research & Publications

    1. Thabrew I, Munasinghe J, Senarath S, Yapa R M S C, “The effects of Cassia auriculata and Cardiospermum halicacabum teas on the steady state blood level of thoephyllin in rats.” Drug metaboliosum and drug interactions 2004; Vol 20 No 4 : 263-271
    2. A K E Goonetileke, T M J Munasinghe, H C Cooray, W K Balasooriya, N Fernando; “Theophyllin blood levels in Sri Lankan asthmatics : comparison of two methods of assay” 2002; 47-2, 50 -51  
    3. M G Thammitiyagoda, M I Thabrew, T.M.J. Munasinghe, W.G.S.S. Kumara, “Investigation of possible lipid lowering properties of Allium porrum ( Leek ) in wistar rats”. Sri Lanka veterinary association 53rd annual convention and scientific sessions 2001. 
    4. Janake Munasinghe, “Need based drug selection. Do we need it - A consumer / prescriber / regulator  view point”. The Sri Lanka Practitioner,  9 : 2000 :17-19
    5. Goonatillke A.K.E., Munasinghe T. M.J., Guruge D.S.H.P., Samaraweera  D.S.N., Weerasena O.V.G.L. “Plasma pharmacokinetics of generic amoxicillin and the innovator brand: a comparison.” The Ceylon Medical Journal 43,  (1998); 16-18 
    6. Janaje Munasinghe, T. M., and D. R. J. Singer. “Costs and Prevention of Adverse Drug Reactions.” European Journal of Internal Medicine 12, no. 5 (September 2001): 403-5.
    7. Liyanage, Chiranthi Kongala, Tilak Manthi Janake Munasinghe, and Adsareswary Paramanantham. “Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis Presenting with Fever and Confusion.” Research article. Case Reports in Neurological Medicine, 2017. https://doi.org/10.1155/2017/3790741.
    8. Munasinghe, T. M. J. “Adverse Drug Reactions: Monitoring, Reporting and Prevention.” Ceylon Medical Journal 47, no. 1 (January 22, 2014): 19-21. https://doi.org/10.4038/cmj.v47i1.6403.
    9. Samarasekara, Keshinie, and Janake Munasinghe. “Dengue Shock Syndrome Complicated with Acute Liver Failure and Kidney Injury, Infective Endocarditis, and Deep Vein Thrombosis: A Case Report.” Journal of Medical Case Reports 12 (October 30, 2018). https://doi.org/10.1186/s13256-018-1862-1.
    10. Thabrew, Ira, Janake Munasinghe, Surekha Chackrewarthi, and Susantha Senarath. “The Effects of Cassia Auriculata and Cardiospermum Halicacabum Teas on the Steady State Blood Level and Toxicity of Carbamazepine.” Journal of Ethnopharmacology 90, no. 1 (January 2004): 145-50.
    11. Thabrew, M. Ira, T. M. Janake Munasinghe, Surekha Chackrewarthi, and Susantha Senarath. “Possible Interaction of Herbal Tea and Carbamazepine.” Drug Metabolism and Drug Interactions 19, no. 3 (2003): 177-87.
    12. Thammitiyagoda, M. G., M. I. Thabrew, T. M. J. Munasinghe, and H. Peiris. “Making a Hypercholesterolaemic Animal Model by Feeding a Diet Containing Cholesterol and Butter to Wistar Rats,” 1999. http://repository.kln.ac.lk/handle/123456789/1412.
    13. Webster, Ruth, Abdul Salam, H. Asita de Silva, Vanessa Selak, Sandrine Stepien, Senaka Rajapakse, Stanley Amarasekara, . et al “Fixed Low-Dose Triple Combination Antihypertensive Medication vs Usual Care for Blood Pressure Control in Patients With Mild to Moderate Hypertension in Sri Lanka: A Randomized Clinical Trial.” JAMA 320, no. 6 (August 14, 2018): 566. https://doi.org/10.1001/jama.2018.10359.
    14. N Ginige, K S H de Silva, J K Wanigasinghe, N S Gunawardane,       T M J Munasinghe. “Effects of long term anti epileptic drugs on serum vitamin D levels and bone profile in a cohort of Sri Lankan children.” International Journal of Paediatric Endocrinology  ( Poster Presentation)  
    15. Seroconversion following vaccination with tetanus toxoid, to diagnose specific antibody deficiency in patients with recurrent infections. Niloofa MJR, Munasinghe TMJ, Senanayake MP, De Silva NR. Annual Academic Sessions 2012 Institute of Biochemistry, Molecular Biology & Biotechnology, University of Colombo
  • Other Publications
  • Other Publications

    Editorial Boards

    •  Medical Research Institute Journal - Co editor
    •  Issues in Medical Ethics - International Advisory Board
    •  Editor for course material for BSc in Pharmacology and Pharcotherapeutics - Open University of Sri     Lanka
    •  Editor for course material for BSc in Nursing - Open University of Sri Lanka
  • Research Interests
  • Research Interests

    • Diabetes
  • Work and Teaching Experience
  • Work and Teaching Experience

    • Consultant Physician National Hospital of Sri Lanka Colombo     2013 - 2017
    • Consultant Clinical Pharmacologist   Dept. of Pharmacology          
    • Head of Department Medical Research Institute Colombo   1991- 2013                                   
    • Honorary Senior Lecturer Faculty of Medicine University of Colombo   2017
    • External examiner M. Phil Faculty of Medicine University of Colombo   2004 - 2008
    • External Examiner in Pharmacology Faculty of Medical Sciences University of Sri Jayewardenepura   2003 & 2005         
    • External Examiner   BSc Human Biology  Faculty of Medical Sciences University of Sri Jayardenepura  2002 & 2005                                             
    • Visiting Lecturer Institute of Biochemistry, Molecular and Cellular Immunology  University of Colombo  2005                                  
    • Examiner in Clinical Medicine   Dip. in Family Medicine Post Graduate Institute of Medicine, University of Colombo 2005   
    • External examiner Molecular and Cellular Immunology Institute of Biochemistry, University of Colombo 2005
    • External examiner MD Medical Administration Postgraduate Institute of Medicine  2015
    • External examiner MD Medicine Postgraduate Institute of Medicine     2016
    • External examiner Faculty of Medicine Final MBBS University of Colombo 2014 - 2017                
    • Supervisor for M Phil. in Pharmacology University of Jaffna 2006
    • Visiting Lecturer in Pharmacology Dept of Pharmacology Faculty of Medicine University of Colombo 1996 - 1997
    • Visiting Lecturer in Pharmacology and Therapeutics General Sir John Kotelawela Defence University 2015 - 2017      
    • Research Assistant   Dept. of Pharmacology and Medicine Niigata University School of  Medicine, Japan 1990 -1991
  • Awards & Grants
  • Awards & Grants

    • Presidential award for research - 2004
  • Presentations and guest lectures
  • Presentations and guest lectures

    1. Sri Lanka College Microbiologists - Annual Scientific Sessions 2016 Symposium - The problem from a clinician's point of view" “Multidrug Resistant Bacterial Infections - How to Combat?”
    2. Sixth Sri Lanka Biennial Conference on Science and Technology ( BICOST VI ) Activities and Plans of the Medical Research Institute
    3. Therapeutic Drug Monitoring Its application to antibiotics
      Plenary Lecture - Sri Lanka College of Microbiologists Annual Academic Sessions 2008
    4. Drug Therapy of Asthma Sri Lanka Medical Association
    5. Drug Therapy of Hypertension . Clinical Society of the Colombo Chest Clinic
    6. Rational Prescribing. Sri Lanka College of General Practitioners
    7. Individualizing dose in aminoglycoside therapy. Sri Lanka College of Microbiologists .
    8. Therapeutic drug Monitoring Its application to aminoglycosisde therapy. Anuradhapura Clinical Society- Sri Lanka Medical Association Jt. Clinical Meeting
    9. Immunoglobulin Therapy .
      Allergy and Immunology Society of Sri Lanka / The Federation of Immunological Societies of Asia - Oceania
    10. Immunotherapy. Allergy and Immunology Society of Sri Lanka
    11. Therapeutic drug monitoring. The College of General Practitioners of Sri Lanka
  • Involvement with other Organizations
  • Involvement with other Organizations

    • Member, Technical Advisory Committee of the Cosmetic Devises and Drugs Authority Ministry of Health , Sri Lanka.
    • Member Advisory committee National Medicines Regulatory Authority ( NMRA)
    • Member, Technical Evaluation Panel of the State Pharmaceuticals Corporation of Sri Lanka.
    • Member, expert committee on Rational Prescribing of Drugs of the Sri Lanka Medical Association. 1997 -1999
    • Member, Drug Evaluation Sub Committee of The Cosmetic Devises and Drug Authority of Sri Lanka.
    • Member, National Committee on Tobacco and Health 1996-1998
    • Secretary, Research Committee- Medical Research Institute
    • Secretary, Ethical Review Committee - Medical Research Institute
    • Member Dietary supplements and Neutraceuticals Sub Committee of the Ministry of Health
    • Adjudicator ( external evaluator ) for post of Professor of Pharmacology University of Colombo 2004
    • Member of National Standing Committee, National Medicinal Drug Regulatory Authority 2006 - 2007
    • Secretary of the Clinical Trials Sub-Committee of the Drug Regulatory Authority Ministry of Health 2009
    • Member of the Committee for Monitoring of Adverse Drug Reactions 2009
    • Member of the Speciality Board in Clinical Pharmacology Post Graduate Institute of Medicine, University of Colombo 2009
    • Member of the Ministerial Committee to investigate into complaints of quality failures of Pharmaceuticals 2009
    • Member of National Steering Committee on the Clinical Trials Initiative in Sri Lanka
    • Member Advisory Committee National Medicines Regulatory Authority ( NMRA)